Sodium Hydroxide → 3-ethoxy-1-methyl-1H-pyrazole-5-carboxylic acid

HRID 1663675

반응식

HRID 1663675 반응식
[CH2:1]([O:3][C:4]1[CH:8]=[C:7]([C:9]([O:11]C)=[O:10])[N:6]([CH3:13])[N:5]=1)[CH3:2].[OH-].[Na+]>CO>[CH2:1]([O:3][C:4]1[CH:8]=[C:7]([C:9]([OH:11])=[O:10])[N:6]([CH3:13])[N:5]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 57441049methyl 3-ethoxy-1-methyl-1H-pyrazole-5-carboxylate

생성물 1

HCID 574410503-ethoxy-1-methyl-1H-pyrazole-5-carboxylic acid수율 81%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Using methyl 3-ethoxy-1-methyl-1H-pyrazole-5-carboxylate (2.59 g, 14.1 mmol), methanol (15 mL) and 8N aqueous sodium hydroxide solution (3.00 mL), and in the same manner as in Reference Example 58, the title compound (1.94 g, yield 81%) was obtained.

출처 및 근거

ORD 기록
ord-57835d67dd354669af6c4eaf6a414f26
출처 데이터셋
uspto-grants-2011_10
특허 번호
US08034812B2

연결된 노트

불러오는 중…