Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetate → 5-Nitro-N-(2-oxo-ethyl)-isophthalamic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | N-(2,2-dimethoxy-ethyl)-5-nitro-isophthalamic acid methyl ester | HCID 67439609 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-Nitro-N-(2-oxo-ethyl)-isophthalamic acid methyl ester | HCID 86626579 | — |
반응 단계
A mixture of 29.7 g (95.1 mmol) of N-(2,2-dimethoxy-ethyl)-5-nitro-isophthalamic acid methyl ester in 300 ml of THF and 300 ml of 2N HCl is stirred overnight. Ethyl acetate is added, and the mixture is washed twice with brine. The organic phase is dried over sodium sulfate and evaporated to yield the product in the form of a yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08039455B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-1612f793da6a4beda7e6ce3a5b6b8e03 |
| 출처 메모 | uspto-grants-2011_10 |