反应详情

A mixture of 29.7 g (95.1 mmol) of N-(2,2-dimethoxy-ethyl)-5-nitro-isophthalamic acid methyl ester in 300 ml of THF and 300 ml of 2N HCl is stirred overnight. Ethyl acetate is added, and the mixture is washed twice with brine. The organic phase is dried over sodium sulfate and evaporated to yield the product in the form of a yellow oil.

1. washthe mixture is washed twice with brine
2. dry with materialThe organic phase is dried over sodium sulfate
3. customevaporated
4. customto yield the product in the form of a yellow oil