Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 4-(3-Benzyloxy-benzylidene)-piperidine trifluoroacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 4-(3-Benzyloxy-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester | HCID 66876001 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-(3-Benzyloxy-benzylidene)-piperidine trifluoroacetate | HCID 66876189 | — |
반응 단계
4-(3-Benzyloxy-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester (534 mg, 1.4 mmol) from Step 2 was dissolved in CH2Cl2 (5 mL) and treated with trifluoroacetic acid (1.05 mL, 14.1 mmol). After 2 hours, the solution was concentrated to provide the title compound which was used without further purification (550 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08044052B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-4fc2c6e0d9814ed1af959ba0dce20d27 |
| 출처 메모 | uspto-grants-2011_10 |