Water → Mupirocin Calcium

HRID 16665

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HRID 16665 반응식
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참가 물질

4

반응물 2

HCID 962WaterHCID 6435927Bactroban2회

생성물 1

HCID 5282317Mupirocin Calcium

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Amorphous mupirocin calcium (5.00 g, 4.80 mmole) was dissolved in methanol (15 ml) and stirred to give a clear solution. Water (10 ml) was added to the solution. Methanol from the solution was evaporated at reduced pressure to give a final volume of 7 ml. The mupirocin calcium solution was allowed to crystallize for 60 h at 5° C. The crystalline product was filtered and washed with water (5 ml). The product was dried at 30° C. for 12 h.

후처리

  1. customto give a clear solution
  2. customMethanol from the solution was evaporated at reduced pressure
  3. customto give a final volume of 7 ml
  4. customto crystallize for 60 h at 5° C
  5. filtrationThe crystalline product was filtered
  6. washwashed with water (5 ml)
  7. customThe product was dried at 30° C. for 12 h.

출처 및 근거

ORD 기록
ord-ec4f4bb3bf064bed92ba29c1ae4fe37f
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07737177B2

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