4'-Trifluoromethyl-biphenyl-3-carbaldehyde → 4'-(Trifluoromethyl)[1,1'-biphenyl]-3-methanol

HRID 1669235노트

반응식

HRID 1669235 반응식
[BH4-].[Na+].[F:3][C:4]([F:20])([F:19])[C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH:17]=[O:18])[CH:12]=2)=[CH:7][CH:6]=1>>[F:3][C:4]([F:19])([F:20])[C:5]1[CH:6]=[CH:7][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH2:17][OH:18])[CH:12]=2)=[CH:9][CH:10]=1

참가 물질

3

반응물 2

HCID 27827114'-Trifluoromethyl-biphenyl-3-carbaldehydeHCID 4311764Sodium borohydride

생성물 1

HCID 144680034'-(Trifluoromethyl)[1,1'-biphenyl]-3-methanol

실험 절차

The titled compound was prepared by standard NaBH4 reduction of 4′-trifluoromethyl-biphenyl-3-carbaldehyde (quant.). 1NMR (400 MHz, CDCl3) δ ppm: 7.40, 7.70 (m, 8H), 4.79 (s, 2H).

출처 및 근거

ORD 기록
ord-2440616816bf4890bf0fc85620416f97
출처 데이터셋
uspto-grants-2011_08
특허 번호
US07989457B2

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