Hydrochloric Acid → HCID 21952711, 화합물
반응식
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9]N.[NH:11]1[CH2:16][CH2:15][C:14](=O)[CH2:13][CH2:12]1.Cl>C(O)C>[CH3:1][S:2][C:3]1[C:4]2[NH:9][C:14]3[CH2:15][CH2:16][NH:11][CH2:12][C:13]=3[C:5]=2[CH:6]=[CH:7][CH:8]=1참가 물질
5
실험 절차
The 2-(methylthio)phenyl hydrazine (5.32 g, 30.0 mmol) and 4-piperidone (4.07 g, 30.0 mmol) were partially dissolved in the ethanol (75 mL) and heated initially to reflux for 1 h. A heavy precipitate formed from the almost clear solution. The reaction was then treated with the conc hydrochloric acid (2.5 mL) and diluted with further ethanol (25 mL) to assist stirring and heating continued for a further 4 h. After cooling to RT overnight the solid was filtered washing isopropanol (25 mL). Obtained 7.70 g
후처리
- temperatureheated initially
- temperatureto reflux for 1 h
- customA heavy precipitate formed from the almost clear solution
- temperatureheating
- filtrationwas filtered
- washwashing isopropanol (25 mL)
- customObtained 7.70 g
출처 및 근거
- ORD 기록
- ord-f238cd7d368b44e6905c72afd2188f9b
- 출처 데이터셋
- uspto-grants-2011_08
- 특허 번호
- US08008279B2
반응 노트
불러오는 중…