Sodium Hydroxide → 4-[5-(Tert-butoxycarbonylamino)-2-methyl-phenyl]benzoic acid

HRID 1678463노트

반응식

HRID 1678463 반응식
C([O:3][C:4]([C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[C:16]([NH:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH:15]=[CH:14][C:13]=2[CH3:26])=[CH:8][CH:7]=1)=[O:5])C.[OH-].[Na+]>C(O)C>[C:22]([O:21][C:19]([NH:18][C:16]1[CH:15]=[CH:14][C:13]([CH3:26])=[C:12]([C:9]2[CH:8]=[CH:7][C:6]([C:4]([OH:5])=[O:3])=[CH:11][CH:10]=2)[CH:17]=1)=[O:20])([CH3:25])([CH3:24])[CH3:23]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 598223705'-tert-Butoxycarbonylamino-2'-methyl-biphenyl-4-carboxylic acid ethyl ester

생성물 1

HCID 598223484-[5-(Tert-butoxycarbonylamino)-2-methyl-phenyl]benzoic acid

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

5′-tert-Butoxycarbonylamino-2′-methyl-biphenyl-4-carboxylic acid ethyl ester (6.3 g) was stirred in ethanol (75 ml) and 1M sodium hydroxide (30 ml) at 20 C for 18 h. The mixture was then acidified and the ethanol evaporated. The pale beige solid thus formed was collected by filtration and dried (4.26 g)

후처리

  1. customthe ethanol evaporated
  2. customThe pale beige solid thus formed
  3. filtrationwas collected by filtration
  4. customdried (4.26 g)

출처 및 근거

ORD 기록
ord-b7aedf9efb6847d9a24fb4e5dd7c8d98
출처 데이터셋
uspto-grants-2011_08
특허 번호
US08008303B2

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