Hydrochloric Acid → 4-(Benzyloxy)benzene-1,2-diamine
반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][C:3]=1[N+:16]([O-])=O.Cl.[OH-].[NH4+]>[Fe].CO>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][C:3]=1[NH2:16]참가 물질
6
실험 절차
2.44 G. of 1-amino-4-benzyloxy-2-nitrobenzene is stirred in 100 ml. methanol and 100 ml. 20% hydrochloric acid with 1.0 g. iron powder at room temperature. After two hours, the mixture is poured into excess ammonium hydroxide solution, the residue extracted with chloroform, filtered under nitrogen, dried over magnesium sulfate, filtered once again, and evaporated to dryness to give 1,2-diamino-4-benzyloxybenzene.
후처리
- customat room temperature
- extractionthe residue extracted with chloroform
- filtrationfiltered under nitrogen
- dry with materialdried over magnesium sulfate
- filtrationfiltered once again
- customevaporated to dryness
출처 및 근거
- ORD 기록
- ord-ba2497dcee00408e8a8915085b5eae18
- 출처 데이터셋
- uspto-grants-1978_03
- 특허 번호
- US04080461
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