Sodium Hydroxide → HCID 23695280, 화합물

HRID 1679507노트

반응식

HRID 1679507 반응식
[Cl:1][CH:2]([CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]([CH3:25])([CH3:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:11][CH:10]=1)[C:3]([O:5]CC)=[O:4].[OH-].[Na+:27]>C(O)C.O>[Cl:1][CH:2]([CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]([CH3:25])([CH3:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:11][CH:10]=1)[C:3]([O-:5])=[O:4].[Na+:27]

참가 물질

5

반응물 2

HCID 14798Sodium HydroxideHCID 194150Ethyl alpha-chloro-4-(2-methyl-2-phenylpropoxy)benzenepropanoate

생성물 1

HCID 23695280HCID 23695280, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

In 15 ml of ethanol is dissolved 3.6 g of ethyl 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionate, and under cooling with ice and stirring, a solution of 0.35 sodium hydroxide in 3.5 ml water is added. The mixture is kept under the same condition for 30 minutes, after which the solution is concentrated to dryness. The residue is dissolved in 10 ml of water, the solution is washed three times with ether, and then the solution is concentrated to dryness. The procedure yields 2.6 g of sodium 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)-phenyl]propionate, as white amorphous substance.

후처리

  1. temperatureunder cooling with ice
  2. concentrationafter which the solution is concentrated to dryness
  3. dissolutionThe residue is dissolved in 10 ml of water
  4. washthe solution is washed three times with ether
  5. concentrationthe solution is concentrated to dryness

출처 및 근거

ORD 기록
ord-c61f1f2068714e40af99166812fd33ab
출처 데이터셋
uspto-grants-1978_03
특허 번호
US04080505

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