2-(2-Pyridiniomethyl)isothiouronium dichloride → Thiourea
반응식
[ClH:1].Cl.[CH2:3]([C:7]1[CH:12]=[CH:11][N:10]=[C:9]([CH2:13][S:14][C:15](=[NH:17])[NH2:16])[CH:8]=1)[CH2:4][CH2:5][CH3:6].Cl.Cl.N1C=CC=CC=1CSC(=N)N>>[ClH:1].[CH2:3]([C:7]1[CH:12]=[CH:11][N:10]=[C:9]([CH2:13][Cl:1])[CH:8]=1)[CH2:4][CH2:5][CH3:6].[NH2:16][C:15]([NH2:17])=[S:14].[ClH:1].[ClH:1].[CH2:3]([C:7]1[CH:12]=[CH:11][N:10]=[C:9]([CH2:13][S:14][C:15](=[NH:16])[NH2:17])[CH:8]=1)[CH2:4][CH2:5][CH3:6]참가 물질
5
실험 절차
2-(4-n-Butylpyrid-2-ylmethyl)isothiourea dihydrochloride can be prepared in accordance with the method described in Example 1 for the preparation of 2-(pyrid-2-ylmethyl)isothiourea dihydrochloride. Using 4-n-butyl-2-chloromethylpyridine hydrochloride (26.9 g) and thiourea (11.3 g) as the starting materials, 2-(4-n-butylpyrid-2-ylmethyl)isothiourea dihydrochloride (26.4 g), melting at 209° C., is obtained.