Hydrazine hydrate (1:1) → 6-Hydrazinyl-5-methoxy-3-pyridinesulfonamide
반응식
Cl[C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([S:10](=[O:13])(=[O:12])[NH2:11])=[CH:4][N:3]=1.O.[NH2:15][NH2:16]>CO>[NH:15]([C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([S:10](=[O:13])(=[O:12])[NH2:11])=[CH:4][N:3]=1)[NH2:16]참가 물질
4
실험 절차
2-Chloro-3-methoxy-5-sulfamoylpyridine (0.3 g, 1.35×10-3 mole) and hydrazine hydrate (0.53 g, approximately 0.01 mole) were added to methanol (20 ml). After refluxing overnight, the reaction mixture was stripped of methanol in vacuo to yield an oil which was cooled in an ice bath and triturated with water (5 ml). The precipitate was collected by filtration and air dried; yield, 0.22 g (75 percent).
후처리
- temperatureAfter refluxing overnight
- customto yield an oil which
- temperaturewas cooled in an ice bath
- customtriturated with water (5 ml)
- filtrationThe precipitate was collected by filtration and air
- customdried
- customyield
출처 및 근거
- ORD 기록
- ord-608a8918b7ad4a2e8c10452b88540f13
- 출처 데이터셋
- uspto-grants-1981_06
- 특허 번호
- US04273706
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