Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Liothyronine → N-Bromoacetyl-3,3',5-triiodothyronine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Liothyronine | HCID 5920 | — |
| 반응물 | Bromoacetyl bromide | HCID 61147 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | N-Bromoacetyl-3,3',5-triiodothyronine | HCID 122086 | — |
반응 단계
According to the present invention a solution of 3,3',5-triiodo-L-thyronine and bromoacetyl bromide in ethyl acetate is refluxed for a period of time to produce the bromoacetylated hormone which is then fractionated by high speed countercurrent chromatography to yield highly pure N-bromoacetyl-3,3',5-triiodo-L-thyronine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05169984 |
| 출처 데이터셋 | uspto-grants-1992_12 |
| ORD ID | ord-5970f06b834348c39766db5e4bc8499b |
| 출처 메모 | uspto-grants-1992_12 |