Water → Acetophenone

HRID 1681449

반응식

[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[CH3:2].O.S([O-])([O-])=[O:11].[Na+].[Na+].[N+]([O-])([O-])=O.[Pb+2].[N+]([O-])([O-])=O>>[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)(=[O:11])[CH3:2]

참가 물질

반응물 4

HCID 962Water

HCID 7500Ethylbenzene

HCID 24437Sodium Sulfite

HCID 24924Lead nitrate

생성물 1

HCID 7410Acetophenone수율 95%

실험 절차

Ten millimoles of ethylbenzene were heated at 400° C. for 1 hour with 1.35 ml of water containing 20 millimoles of sodium sulfite and 10 millimoles of lead nitrate. On cooling, a suspension of black precipitate was observed. The reaction product was extracted with ether and the ether layer was dried over Na2SO4 and concentrated to yield acetophenone in more than 95% yield. Acetophenone was confirmed by NMR and gas chromatographic techniques.

후처리

temperatureOn cooling
additiona suspension of black precipitate
extractionThe reaction product was extracted with ether
dry with materialthe ether layer was dried over Na2SO4
concentrationconcentrated

출처 및 근거

ORD 기록: ord-f2ef92410e4545f4b0b37e77be1d5962
출처 데이터셋: uspto-grants-1992_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05171880

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