LY 213024 → HCID 72738706, 화합물

HRID 1681548노트

반응식

HRID 1681548 반응식
[C:1]([C:4]1[CH:5]=[C:6]([CH:31]=[CH:32][CH:33]=1)[C:7]([C:9]1[CH:10]=[CH:11][C:12]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[C:13]([CH2:15][CH2:16][C:17]([OH:19])=[O:18])[CH:14]=1)=O)([OH:3])=[O:2].Cl.[NH2:35][OH:36]>>[C:1]([C:4]1[CH:5]=[C:6]([C:7](=[N:35][OH:36])[C:9]2[CH:10]=[CH:11][C:12]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[C:13]([CH2:15][CH2:16][C:17]([OH:19])=[O:18])[CH:14]=2)[CH:31]=[CH:32][CH:33]=1)([OH:3])=[O:2]

참가 물질

3

반응물 2

HCID 195214LY 213024HCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 72738706HCID 72738706, 화합물수율 81%

실험 절차

The title product was also prepared in 81% yield directly from 5-(3-carboxybenzoyl)-2-(decyloxy)benzenepropanoic acid upon treatment with hydroxylamine hydrochloride according to the procedure of Example 51.

출처 및 근거

ORD 기록
ord-f730cce711164a56b5e75a3ec6ab8024
출처 데이터셋
uspto-grants-1992_12
특허 번호
US05171882

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