6,7-Dimethyl-3,4-dihydroisoquinolin-1(2H)-one → HCID 19803496, 화합물
반응식
[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[CH3:12])[C:8](=[O:13])[NH:7][CH2:6][CH2:5]2.CC(C)([O-])C.[K+].[Cl:20][CH2:21][CH:22]1[CH2:27][CH2:26][CH2:25][N:24]([CH2:28][CH2:29][C:30]2[C:39]3[C:34](=[CH:35][C:36]([O:42][CH3:43])=[C:37]([O:40][CH3:41])[CH:38]=3)[CH:33]=[N:32][CH:31]=2)[CH2:23]1>CS(C)=O>[ClH:20].[ClH:20].[CH3:41][O:40][C:37]1[CH:38]=[C:39]2[C:34](=[CH:35][C:36]=1[O:42][CH3:43])[CH:33]=[N:32][CH:31]=[C:30]2[CH2:29][CH2:28][N:24]1[CH2:25][CH2:26][CH2:27][CH:22]([CH2:21][N:7]2[CH2:6][CH2:5][C:4]3[C:9](=[CH:10][C:11]([CH3:12])=[C:2]([CH3:1])[CH:3]=3)[C:8]2=[O:13])[CH2:23]1참가 물질
5
실험 절차
Prepared from 6,7-dimethyl-1-oxo-1,2,3,4-tetrahydro-isoquinoline in dimethylsulphoxide with potassium tert.butoxide and 3-chloromethyl-N-[2-(6,7-dimethoxy-isoquinol-4-yl)-ethyl]-piperidine analogously to Example 2.