Hydroxylamine HCl → HCID 189199, 화합물

HRID 1683737노트

반응식

HRID 1683737 반응식
[CH:1](=[C:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C:9]1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl-].[OH:16][NH3+:17]>C(O)C>[CH:1](=[C:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C:9]1=[N:17][OH:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 21645Hydroxylamine HClHCID 989262-Benzylidenecyclohexanone

생성물 1

HCID 189199HCID 189199, 화합물수율 97.8%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 2-benzylidenecyclohexanone (3.5 g, 18.8 mmol, J. Chem. Soc. 1949, 2957), hydroxylammonium chloride (3.9 g, 56 mmol) and ethanol (50 ml) was stirred at ambient temperature for 3 days. The solvent was evaporated in vacuo and the residue was dissolved in a mixture of ethyl acetate (200 ml) and water (50 ml). The phases were separated and the aqueous phase was extracted with ethyl acetate (50 ml). The combined organic extracts were washed with water and dried (MgSO4). The solvent was evaporated in vacuo to give 3.7 g of 2-benzylidenecyclohexanone oxime as a solid. M.p. 114°-115° C.

후처리

  1. customThe solvent was evaporated in vacuo
  2. dissolutionthe residue was dissolved in a mixture of ethyl acetate (200 ml) and water (50 ml)
  3. customThe phases were separated
  4. extractionthe aqueous phase was extracted with ethyl acetate (50 ml)
  5. washThe combined organic extracts were washed with water
  6. dry with materialdried (MgSO4)
  7. customThe solvent was evaporated in vacuo

출처 및 근거

ORD 기록
ord-cf68406217e949d2857bab85922d0897
출처 데이터셋
uspto-grants-1997_06
특허 번호
US05639766

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