Hydroxylamine HCl
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5470-11-1[Cl-].[NH3+]OWCYJQVALWQMJGE-UHFFFAOYSA-MSee also: Hydroxyamine hydrochloride (annotation moved to).
5470-11-1DTXSID7025425Hydroxylamine Hydrochloride(NH2OH.HCl) is an inorganic compound that is the hydrochloric acid salt of hydroxylamine. It is highly hygroscopic and decomposes when exposed to dampness above 151℃. This compound is primarily used as a reducing agent and imaging agent and is instrumental in the preparation of oximes in organic synthesis. It can convert aldehydes and ketones to oximes and acid chlorides to hydroxamic acids. However, This product is highly toxic and irritating to the skin.
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
용도이 제품은 항암제 (hydroxyurea), sulfamethylamine (sulfamide) 및 살충제 (methomyl)의 합성 원료뿐만 아니라 유기 합성에서 옥심의 제조에 사용되는 환원제 및 이미징 제로 주로 사용됩니다. 그것은 전기 분석에서 depolarization 에이전트 및 합성 고무 산업에서 비 착색 단기 정지 에이전트로 사용됩니다. 제약 업계는 nenomine의 중간체로 사용됩니다. 합성 염료는 indirubin 중간체의 제조에 사용됩니다. 그리스 산업은 지방산과 비누의 산화 방지제로 사용됩니다. 분석 화학은 포름 알데히드, 푸르 푸랄, 녹나무 및 포도당의 분석에 사용됩니다. 전기 화학 분석에서의 탈분극. 또한 철과 강철의 마그네슘 측정, 설 폰산과 지방산의 미량 분석, 알데히드와 케톤의 측정 및 탈 극성 화제로 사용됩니다. 또한, 컬러 필름 현상 등에도 사용됩니다.
개요Hydroxylamine hydrochloride is a reducing agent that is routinely used for the deacetylation of SATA to form free sulfhydryls (Figure 1), for cleavage of protein cross‐linkers that contain carbonyl groups (i.e. EGS) and for mutagenesis of plasmid DNA.Hydroxylamine converts aldehydes and ketones (carbonyls) to their oxime derivative in weak bases, therefore cross‐linkers and other compounds with carbonyl groups are cleavable with Hydroxylamine hydrochloride.SATA and SATP are modification reagents that add a sulfhydryl group to primary amines on biomolecules. The initial modification results in the addition of an acetyl‐protected sulfur enabling storage of the biomolecule. To generate a free sulfhydryl the biomolecule is treated with hydroxylamine to remove the protecting acetyl group (see figure).EGS and sulfo‐EGS are homobifunctional, succinimidyl ester, amine reactive crosslinkers that are resistant to cleavage by denaturants used in SDS‐PAGE conditions, but may be cleaved with hydroxylamine.
용도Hydroxylamine hydrochloride is a monomoamine oxidase inhibitor. It is used to prepare oximes and hydroxmic acids in organic synthesis. It acts as a copolymerization inhibitor. It can be used to remove bromine and polybromide from a solution during extraction of lignin from lignocellulosic biomass. It is key starting material for the preparation of pharmaceuticals and agrochemicals. It plays a vital role in rubber and plastic industries as an antioxidant, a vulcanization accelerator and a radical scavenger. It is also used as a color stabilizer and emulsion additive in color films.
일반 설명Hydroxylamine hydrochloride appears as colorless or off-white crystalline solid. pH (0.1 molar aqueous solution) 3.4. pH (0.2 molar aqueous solution) 3.2. (NTP, 1992)
Hydroxylamine hydrochloride is prepared by electrolytic reduction of ammonium chloride. Or by the action of nitromethane with hydrochloric acid and water to obtain hydroxylamine hydrochloride.
정의ChEBI: Hydroxylamine hydrochloride is an organic molecular entity. It is a colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide.
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