Hydrogen Bromide → Methyl 2-(4-chloro-3-hydroxyphenyl)propanoate

HRID 1686383노트

반응식

HRID 1686383 반응식
Br.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH3:14])[C:10]([O:12][CH3:13])=[O:11])=[CH:5][C:4]=1[O:15]C>C(O)(=O)C>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH3:14])[C:10]([O:12][CH3:13])=[O:11])=[CH:5][C:4]=1[OH:15]

참가 물질

4

반응물 2

HCID 260Hydrogen BromideHCID 67266387Methyl 2-(4-chloro-3-methoxyphenyl)propanoate

생성물 1

HCID 67266160Methyl 2-(4-chloro-3-hydroxyphenyl)propanoate

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
100 °C

실험 절차

48% aqueous HBr (10 ml) was added to the product of step (ii) (0.21 g) in acetic acid (10 ml) and heated at 100° C. for 10 h.

출처 및 근거

ORD 기록
ord-08b907b200b04506b83085a08c1e6f4e
출처 데이터셋
uspto-grants-2012_04
특허 번호
US08148572B2

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