Hydrochloric Acid → 3-Amino-2-(thiophen-3-yl)propanoic acid
반응식
O=C1C2C(=CC=CC=2)C(=O)[N:3]1[CH2:12][CH:13]([C:18]1[CH:22]=[CH:21][S:20][CH:19]=1)[C:14]([O:16]C)=[O:15].Cl>>[NH2:3][CH2:12][CH:13]([C:18]1[CH:22]=[CH:21][S:20][CH:19]=1)[C:14]([OH:16])=[O:15]참가 물질
3
실험 절차
To methyl 3-(1,3-dioxoisoindolin-2-yl)-2-(thiophen-3-yl)propanoate (E45) was added 6 N HCl, and the solution was refluxed for 4 hours. The solvents were evaporated to give 3-amino-2-(thiophen-3-yl)propanoic acid (E46).
후처리
- temperaturethe solution was refluxed for 4 hours
- customThe solvents were evaporated
출처 및 근거
- ORD 기록
- ord-7a781bda5c2d4e04bf8b7de6989c0285
- 출처 데이터셋
- uspto-grants-2012_04
- 특허 번호
- US08153656B2
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