N-methyl-2-pyrrolidone → 2-Acetyl-N-((R)-1-(2-fluoro-5-methyl-4-(methylsulfonamido)phenyl)ethyl)-5,6,7,8-tetrahydroquinoline-6-carboxamide

반응식

Cl.[NH2:2][C@@H:3]([C:5]1[C:10]([F:11])=[CH:9][C:8]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])=[C:7]([CH3:17])[CH:6]=1)[CH3:4].[C:18]([C:21]1[CH:30]=[CH:29][C:28]2[CH2:27][CH:26]([C:31](O)=[O:32])[CH2:25][CH2:24][C:23]=2[N:22]=1)(=[O:20])[CH3:19].F[P-](F)(F)(F)(F)F.C[N+](C)=C(N(C)C)ON1C2N=CC=CC=2N=N1.CN1CCCC1=O.C(N(CC)C(C)C)(C)C>CCOC(C)=O>[C:18]([C:21]1[CH:30]=[CH:29][C:28]2[CH2:27][CH:26]([C:31]([NH:2][C@@H:3]([C:5]3[CH:6]=[C:7]([CH3:17])[C:8]([NH:12][S:13]([CH3:16])(=[O:15])=[O:14])=[CH:9][C:10]=3[F:11])[CH3:4])=[O:32])[CH2:25][CH2:24][C:23]=2[N:22]=1)(=[O:20])[CH3:19]