참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Bromopropionitrile | HCID 140538 | — |
| 반응물 | (2-Nitrophenyl)methanamine | HCID 423893 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2-(1-(2-Nitrophenyl)ethylamino)acetonitrile | HCID 86625228 | — |
반응 단계
2-Nitrobenzylamine (513 mg, 3.37 mmol) was added to an acetonitrile (40 mL) containing K2CO3 (932 mg, 6.74 mmol) and 2-bromopropanitrile (677 mg, 5.06 mmol) under a nitrogen atmosphere. The reaction mixture was heated to 65° C. for 14 hours. The product (18) was used without purification or concentration in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08163738B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_04 |
|---|
| ORD ID | ord-8046259b90de42408c5cb640d8abaafc |
|---|
| 출처 메모 | uspto-grants-2012_04 |
|---|
