Isobutyronitrile → 5-chloro-2,2-dimethylpentanenitrile

HRID 1699119노트

반응식

HRID 1699119 반응식
[C:1](#[N:5])[CH:2]([CH3:4])[CH3:3].Br[CH2:7][CH2:8][CH2:9][Cl:10]>>[Cl:10][CH2:9][CH2:8][CH2:7][C:2]([CH3:4])([CH3:3])[C:1]#[N:5]

참가 물질

3

반응물 2

HCID 6559IsobutyronitrileHCID 80061-Bromo-3-chloropropane

생성물 1

HCID 2642175-chloro-2,2-dimethylpentanenitrile

실험 절차

reacting isobutyronitrile with 1-bromo-3-chloropropane in the presence of a first base in a non-polar solvent at a temperature of about 15°to 65°C. to afford 5-chloro-2,2-dimethylpentanenitrile;

후처리

  1. customof about 15°to 65°C.

출처 및 근거

ORD 기록
ord-78beef2858274801a207cbab4e15eac3
출처 데이터셋
uspto-grants-2002_02
특허 번호
US06344580B1

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