Ammonium Acetate → 1-Amino-5-(2,3-dichlorophenyl)cyclohexen-3-one
반응식
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:14][C:13](=O)[CH2:12][C:11](=[O:16])[CH2:10]1.C([O-])(=O)C.[NH4+:21]>C(O)C>[NH2:21][C:13]1[CH2:14][CH:9]([C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([Cl:8])[C:2]=2[Cl:1])[CH2:10][C:11](=[O:16])[CH:12]=1참가 물질
4
실험 절차
A mixture of 5-(2,3-dichlorophenyl)cyclohexane-1,3-dione (1.8 g) and ammonium acetate (1.7 g) in ethanol (20 ml) was refluxed for 14 hours, and the reaction solution was concentrated under reduced pressure. To the residue was added water (20 ml), and the resulting crystals were filtered. The crystals were washed with water and toluene, and dried to give 1-amino-5-(2,3-dichlorophenyl)cyclohexen-3-one (1.6 g) as pale yellow crystals.
후처리
- temperaturewas refluxed for 14 hours
- concentrationthe reaction solution was concentrated under reduced pressure
- additionTo the residue was added water (20 ml)
- filtrationthe resulting crystals were filtered
- washThe crystals were washed with water and toluene
- customdried
출처 및 근거
- ORD 기록
- ord-75975a1469fb4bb790a33048dc41b484
- 출처 데이터셋
- uspto-grants-2002_02
- 특허 번호
- US06350749B1
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