Ammonia → HCID 20346679, 화합물

160 g (1 mol) of 3-methyl-5-phenyl-2-pyrazoline (according to S. G. Beech et al, J. Chem. Soc. (1952) 4,686-90) are hydrogenated with 20 g of freshly prepared Raney nickel in 400 ml of methanol saturated with NH3 for 6 hours at 80° C./100 atmospheres. The catalyst is separated off, the solvent is removed in a rotary evaporator and the product is distilled under a high vacuum. Fractionation of the distillate in a 25 cm Vigreux column gives 151 g=92% of theory of a colourless oil with a boiling point under 0.03 mm of 90°-91° C. C10H16N2 . (164.24)

1. customThe catalyst is separated off
2. customthe solvent is removed in a rotary evaporator
3. distillationthe product is distilled under a high vacuum
4. customFractionation of the distillate in a 25 cm Vigreux column gives 151 g=92% of theory of a colourless oil with a boiling point under 0.03 mm of 90°-91° C

ORD 기록

ord-7614208fe75848b0ad2157b13d9ac585

출처 데이터셋

uspto-grants-1980_03

DOI

10.6084/m9.figshare.5104873.v1

특허 번호

US04193905