Bromine → alpha-Bromo-3-chloropropiophenone

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([C:8](=[O:11])[CH2:9][CH3:10])[CH:5]=[CH:6][CH:7]=1.[Br:12]Br>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8](=[O:11])[CH:9]([Br:12])[CH3:10])[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 24408Bromine2회

HCID 5871283'-Chloropropiophenone

생성물 1

HCID 4992116alpha-Bromo-3-chloropropiophenone

실험 절차

To 1 mole of m-chloropropiophenone heated to 85±5° C., bromine was added dropwise under stirring. The reaction temperature was kept at 85±5° C. during and after the addition of bromine, and the reaction was carried on for 2 hours. Then m-chloro-α-bromopropiophenone (compound of formula (II)) was obtained.

후처리

customwas kept at 85±5° C.
customwas carried on for 2 hours

출처 및 근거

ORD 기록: ord-f3db7bb05d2f478a806fe6b5641ed89b
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07737302B2

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