Hydrochloric Acid → HCID 13036368, 화합물

HRID 1703167노트

반응식

HRID 1703167 반응식
[N:1]1[C:5]2=[CH:6][CH:7]=[CH:8][CH:9]=[CH:10][C:4]2=[N:3][C:2]=1[N:11]1[CH2:16][CH2:15][N:14](C=O)[CH2:13][CH2:12]1.Cl>C(O)C>[N:11]1([C:2]2[N:3]=[C:4]3[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=[C:5]3[N:1]=2)[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 13036367HCID 13036367, 화합물

생성물 1

HCID 13036368HCID 13036368, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 4-(cycloheptimidazol-2-yl)-1-piperazinecarboxaldehyde (38 g) in a solution of 500 ml of 2 N hydrogen chloride in ethanol was refluxed for 6 hr and allowed to stand at room temperature for 18 hr. The precipitate was collected and dried to give the title compound as the hydrochloride salt (31 g): mp>280° C. and nmr(DMSO-d6) δ 3.37 (t, 4H), 4.3 (t, 4H), 8.4 (m, 5H) and 10.0 (s, 2H).

후처리

  1. customThe precipitate was collected
  2. customdried

출처 및 근거

ORD 기록
ord-be18322fbbd54eb0bf8c796b960a4f33
출처 데이터셋
uspto-grants-1982_09
특허 번호
US04351832

반응 노트

불러오는 중…