Hydrogen Bromide → 4,5-Dimethylbenzene-1,2-diol
반응식
[CH3:1][C:2]1[CH:3]=[C:4]([O:11]C)[C:5]([O:9]C)=[CH:6][C:7]=1[CH3:8].Br>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:3]=[C:4]([OH:11])[C:5](=[CH:6][C:7]=1[CH3:8])[OH:9]참가 물질
4
실험 절차
53 g of 4,5-dimethylveratrol (prepared by the method of Bruce, et al., J. Chem. Soc., 1956, 3824-29) was mixed with 200 ml of 48% hydrobromic acid. The mixture was stirred at reflux temperature, in a nitrogen atmosphere, for 4.5 hours. The crude mixture was heated with 200 ml of toluene. The toluene phase was separated and cooled, to give 4,5-dimethylcatechol (6A), as a solid, mp: 86°-87° C.
후처리
- temperatureat reflux temperature
- customThe toluene phase was separated
- temperaturecooled
출처 및 근거
- ORD 기록
- ord-142956469dcc4d00b6e6b6945384307c
- 출처 데이터셋
- uspto-grants-1980_06
- 특허 번호
- US04208424
반응 노트
불러오는 중…