HCID 18962092, 화합물 → HCID 22989092, 화합물
반응식
C(OC([N:8]([S:64]([C:67]1[CH:72]=[CH:71][C:70]([CH3:73])=[CH:69][CH:68]=1)(=[O:66])=[O:65])[CH2:9][CH2:10][CH2:11][CH2:12][N:13]([S:54]([C:57]1[CH:62]=[CH:61][C:60]([CH3:63])=[CH:59][CH:58]=1)(=[O:56])=[O:55])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N:21]([S:44]([C:47]1[CH:52]=[CH:51][C:50]([CH3:53])=[CH:49][CH:48]=1)(=[O:46])=[O:45])[CH2:22][CH2:23][CH2:24][CH2:25][N:26](C(OC(C)(C)C)=O)[S:27]([C:30]1[CH:35]=[CH:34][C:33]([CH3:36])=[CH:32][CH:31]=1)(=[O:29])=[O:28])=O)(C)(C)C>Cl>[CH3:73][C:70]1[CH:71]=[CH:72][C:67]([S:64]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]([S:54]([C:57]2[CH:58]=[CH:59][C:60]([CH3:63])=[CH:61][CH:62]=2)(=[O:56])=[O:55])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N:21]([S:44]([C:47]2[CH:48]=[CH:49][C:50]([CH3:53])=[CH:51][CH:52]=2)(=[O:46])=[O:45])[CH2:22][CH2:23][CH2:24][CH2:25][NH:26][S:27]([C:30]2[CH:35]=[CH:34][C:33]([CH3:36])=[CH:32][CH:31]=2)(=[O:29])=[O:28])(=[O:66])=[O:65])=[CH:68][CH:69]=1참가 물질
3
실험 절차
Dissolve 1,19-bis(t-butyloxycarbonyl)-1,6,14,19-tetra[(4-methylphenyl)sulfonyl]-1,6,14,19-tetraazanonadecane (11.7 g, 10 mmol) in saturated methanolic hydrochloric acid (100 mL). Stir for several hours and evaporate the solvent in vacuo. Dissolve the residue in water and neutralize with saturated sodium hydrogen carbonate and extract with ethyl acetate. Dry (MgSO4) and evaporate the solvent in vacuo. Purify by silica gel chromatography to give the title compound.
후처리
- customevaporate the solvent in vacuo
- dissolutionDissolve the residue in water