(Dimethylamino)ethyl methacrylate → 4-Benzoyl-N,N-dimethyl-N-(2-(2-methyl-1-oxo-2-propenyloxy)ethyl)benzenemethanaminium chloride

HRID 1709277

반응식

HRID 1709277 반응식
[C:1]([O:6][CH2:7][CH2:8][N:9]([CH3:11])[CH3:10])(=[O:5])[C:2]([CH3:4])=[CH2:3].[Cl:12][CH2:13][C:14]1[CH:27]=[CH:26][C:17]([C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:19])=[CH:16][CH:15]=1>CC(C)=O>[Cl-:12].[C:18]([C:17]1[CH:26]=[CH:27][C:14]([CH2:13][N+:9]([CH3:11])([CH3:10])[CH2:8][CH2:7][O:6][C:1](=[O:5])[C:2]([CH3:4])=[CH2:3])=[CH:15][CH:16]=1)(=[O:19])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

참가 물질

4

반응물 2

HCID 17869(Dimethylamino)ethyl methacrylateHCID 30163764-(Chloromethyl)benzophenone

생성물 1

HCID 867441444-Benzoyl-N,N-dimethyl-N-(2-(2-methyl-1-oxo-2-propenyloxy)ethyl)benzenemethanaminium chloride

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Dimethylaminoethyl methacrylate (10.13 mls) was added to a stirred solution of 4-chloromethylbenzophenone (11.52g) in acetone (50 mls) at 48° C. and the mixture was stirred for fifteen hours at 48°±2° C. The stirred mixture was cooled in an ice bath for two hours prior to filtration, washing with acetone (X2) and drying under vacuo at room temperature. The crude title compound was obtained as a white crystalline solid (16.82g; m.p. 163°-166° C.) which was recrystallised from a mixture of acetone (30 mls) and isopropanol (30 mls).

후처리

  1. temperatureThe stirred mixture was cooled in an ice bath for two hours
  2. filtrationto filtration
  3. washwashing with acetone (X2)
  4. customdrying under vacuo at room temperature

출처 및 근거

ORD 기록
ord-a8edc93285a14aa18dd18de117b26d5b
출처 데이터셋
uspto-grants-1990_08
특허 번호
US04948819

연결된 노트

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