참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | Pyridine, 2,4,6-trichloro- | HCID 27665 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2,6-Dichloro-N-methylpyridin-4-amine | HCID 19957394 | — |
반응 단계
2,4,6-Trichloropyridine (1800 g, 9.89 mol) was dissolved in ethanol (1800 mL). Methylamine 40% solution in ethanol (6.3 L) was added over 1 h and 40 min maintaining the reaction temperature between 20-25° C. The reaction was stirred for 14 hours at room temperature and concentrated. The product was filtered, washed with methyl t-butyl ether (1,500 ml) and dried to yield A1.6 (1200 g, 68%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07737279B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_06 |
|---|
| ORD ID | ord-336a37a99c754ec081c44405c93b39d8 |
|---|
| 출처 메모 | uspto-grants-2010_06 |
|---|
