Octanoic Acid → Sodium octanoate

HRID 1709718

반응식

HRID 1709718 반응식
[C:1]([OH:10])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[OH-].[Na+:12].Cl[CH:14]([OH:16])[CH3:15]>C1(C)C(C)=CC=CC=1.O.C(OCCO)C>[C:1]([O-:10])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[Na+:12].[C:1]([O:10][CH2:15][CH2:14][OH:16])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

참가 물질

8

반응물 3

HCID 379Octanoic AcidHCID 14798Sodium HydroxideHCID 126390351-Chloroethan-1-ol

생성물 2

HCID 170609Polyethylene glycol monocaprylate수율 66%HCID 23664772Sodium octanoate수율 200%

시약·촉매·용매 3

HCID 962Water용매2회HCID 7237O-Xylene용매HCID 8076Glycol monoethyl ether용매

실험 절차

Sodium caprylate (2 mol) was prepared by neutralization of caprylic acid (2 mol; 288.4 g; 317.4 ml) in 750 ml xylene with sodium hydroxide (2 mol; 80 g) in water (160 ml). The reaction mixture was freed of water and then heated with chloroethanol (2.1 mol; 170 g; 204.4 ml) with addition of 2-ethoxyethanol (1000 ml) as a solvent under reflux for 28 hours. The precipitated NaCl was filtered off and washed with 2-ethoxyethanol. The filtrate was distilled and 66% of 2-hydroxyethyl caprylate was obtained; b.p. 141° C./266 Pa. Elemental analysis for C10H20O3 theory: 63.79% C, 10.71% H; found: 63.54% C, 10.93% H. The structure was confirmed by infrared and 13C--NMR spectroscopy. Further procedure was carried out according to example 1.

후처리

  1. temperatureunder reflux for 28 hours
  2. filtrationThe precipitated NaCl was filtered off
  3. washwashed with 2-ethoxyethanol
  4. distillationThe filtrate was distilled

출처 및 근거

ORD 기록
ord-3843656f81504d3aa5c85d89606e3134
출처 데이터셋
uspto-grants-1990_08
특허 번호
US04950733

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