Methyl iodide → HCID 178503338, 화합물

HRID 1710808노트

반응식

HRID 1710808 반응식
[CH3:1][I:2].[Cl:3][C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]([CH3:15])[NH:7][C:8](=[S:14])[NH:9]2>CC(C)=O>[IH:2].[Cl:3][C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]([CH3:15])[NH:7][C:8]([S:14][CH3:1])=[N:9]2

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 86609751HCID 86609751, 화합물

생성물 1

HCID 178503338HCID 178503338, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Methyl iodide (1.16 ml, 19 mmol) was added to a suspension of 5-chloro-4-methyl-3,4-dihydro-1H-quinazoline-2-thione (1.32 g, 6.2 mmol) in acetone (15 ml), and the mixture was stirred at r.t. over the weekend (the reaction is usually complete after 12 h). The precipitated product (2.08 g, 87%) was sufficiently pure for the next step.

출처 및 근거

ORD 기록
ord-cadcc21c206042fdaeddda56346e1729
출처 데이터셋
uspto-grants-2010_09
특허 번호
US07790732B2

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