Hydrochloric Acid → HCID 66877005, 화합물
반응식
C([O:5][C:6](=[O:23])[CH2:7][N:8]1[CH2:17][C:16]2[N:15]=[CH:14][C:13]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:12][C:11]=2[CH2:10][CH2:9]1)(C)(C)C.[ClH:24]>O1CCOCC1>[ClH:24].[CH2:21]([O:20][C:18]([C:13]1[CH:14]=[N:15][C:16]2[CH2:17][N:8]([CH2:7][C:6]([OH:23])=[O:5])[CH2:9][CH2:10][C:11]=2[CH:12]=1)=[O:19])[CH3:22]참가 물질
4
실험 절차
To a solution of ethyl 7-(2-tert-butoxy-2-oxoethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate (657 mg, 2.05 mmol) in dioxane (10 mL) is added 4 N HCl in dioxane (5 ml, 20 mmol) and the mixture is stirred at rt overnight. The solvent is removed and the residue is washed with ether to give the title compound as a white solid. MS (M+1): 265.1.
후처리
- customThe solvent is removed
- washthe residue is washed with ether
출처 및 근거
- ORD 기록
- ord-a26bb9e55ff44f63bfd8c219250993e5
- 출처 데이터셋
- uspto-grants-2010_09
- 특허 번호
- US07795262B2
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