Methyl bromoacetate → Methyl (4-nitro-1-imidazolyl)acetate

HRID 1714279노트

반응식

[N+:1]([C:4]1[N:5]=[CH:6][NH:7][CH:8]=1)([O-:3])=[O:2].[CH3:9][O:10][C:11](=[O:14])[CH2:12]Br>>[CH3:9][O:10][C:11](=[O:14])[CH2:12][N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[N:5]=[CH:6]1

참가 물질

반응물 2

HCID 60984Methyl bromoacetate

HCID 178526856HCID 178526856, 화합물

생성물 1

HCID 3103698Methyl (4-nitro-1-imidazolyl)acetate

실험 절차

4-nitroimidazole was alkylated with bromo-acetic acid methyl ester to provide the title compound: 1H NMR (400 MHz) 3.82 (s, 1H), 4.80, (s, 2H), 7.47 (d, 1H, J=1.7 Hz), 7.84 (d, 1H, J=1.7 Hz); gc/ms m/z 185 (M).

출처 및 근거

ORD 기록: ord-f63c817c82e4476abfab435e6bead2d6
출처 데이터셋: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07795447B2

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