Water → HCID 802571, 화합물
반응식
[NH2:1][N:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[C:3]1[S-:13].[K+].[CH3:15]I.O>CN(C)C=O>[NH2:1][N:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[C:3]1[S:13][CH3:15]참가 물질
5
실험 절차
To a solution 209 mg of potassium 3-amino-3H-quinazolin-4-one-2-thiolate in 5 ml of dimethylformamide, 141 mg of methyl iodide was added, and stirred for 20 minutes at room temperature. Water was added to the solution, followed by extraction with ethyl acetate and drying over anhydrous magnesium sulfate. Distilling the solvent off under reduced pressure, 161 mg (86%) of 3-amino-2-methylthio-3H-quinazolin-4-one was obtained.
후처리
- extractionfollowed by extraction with ethyl acetate
- dry with materialdrying over anhydrous magnesium sulfate
- distillationDistilling the solvent off under reduced pressure
출처 및 근거
- ORD 기록
- ord-78a64271e5e54bdf9227a2a1138c65e4
- 출처 데이터셋
- uspto-grants-2010_09
- 특허 번호
- US07799775B2
반응 노트
불러오는 중…