Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-acetyl-S-(2-aminophenyl)cysteine → 5,1-Benzothiazepine-2-one, 3-acetylamino-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-acetyl-S-(2-aminophenyl)cysteine | HCID 57145208 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | 5,1-Benzothiazepine-2-one, 3-acetylamino- | HCID 539362 | 71.7% |
반응 단계
1.2 g of N-acetyl-S-(2-aminophenyl)cysteine was dissolved in 20 ml of xylene and the resulting solution was heated under reflux for 2 hours. After cooling, the precipitated crystals were separated and washed with methanol to obtain 0.8 g of the desired compound, or 3-acetylamino-2,3-dihydro-1,5-benzothiazepin-4(5H)-one. Its melting point was 283°-286° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04539151 |
| 출처 데이터셋 | uspto-grants-1985_09 |
| ORD ID | ord-69814e6d39a44174a436f6162e7f9839 |
| 출처 메모 | uspto-grants-1985_09 |