Glycerol → Glycerol Monooleate 1.2-Hexadecanediol

HRID 1719659

반응식

HRID 1719659 반응식
[C:1]([O:20][CH2:21][CH:22]([CH2:24][OH:25])[OH:23])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].OCC(CO)O.[CH2:32]([OH:49])[CH:33]([OH:48])[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47].B(O)(O)O>O.C1(C)C=CC=CC=1>[C:1]([O:20][CH2:21][CH:22]([CH2:24][OH:25])[OH:23])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH2:32]([OH:49])[CH:33]([OH:48])[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47]

참가 물질

7

반응물 4

HCID 753Glycerol2회HCID 7628Boric AcidHCID 980371,2-HexadecanediolHCID 5283468Glyceryl Monooleate

생성물 1

HCID 131713685Glycerol Monooleate 1.2-Hexadecanediol

시약·촉매·용매 2

HCID 962Water용매HCID 1140Toluene용매

실험 절차

Approximately 92 g of glycerol monooleate (commercially available as 60/40 mixture of glycerol monoleate/glycerol diooleate), 52 g of 1,2-hexadecanediol and 100 g of toluene were charged to a reactor equipped as described in Example 1. The contents were heated to liquify and 11 g of boric acid were added. The mixture was further heated up to 150° C. over a period of 6 hours until water evolution stopped. Approximately 9 ml. of water collected. The solvent was removed by vacuum distillation at 150° C. and the product was filtered at about 100° C. through diatomaceous earth. The product became a waxy solid after cooling.

후처리

  1. additionwere charged to a reactor
  2. customequipped
  3. temperatureThe contents were heated
  4. customof water collected
  5. customThe solvent was removed by vacuum distillation at 150° C.
  6. filtrationthe product was filtered at about 100° C. through diatomaceous earth
  7. temperatureafter cooling

출처 및 근거

ORD 기록
ord-d460ab393b8a47b9972578c21a6c1841
출처 데이터셋
uspto-grants-1985_09
특허 번호
US04541941

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