Glyceryl Monooleate (HCID 5283468)

개요

1-oleoylglycerol is a 1-monoglyceride where the acyl group is oleoyl. It has a role as a plant metabolite. It is a 1-acylglycerol 18:1 and a monooleoylglycerol. It is functionally related to an oleic acid.

이름 및 식별자

우선 이름: Glyceryl Monooleate
IUPAC: 2,3-dihydroxypropyl (Z)-octadec-9-enoate
현지명: 글리세롤 1-올레이트
영어명: Glyceryl Monooleate
분자식: C21H40O4
분자량: 356.54

이름 및 동의어

MonooleinGlyceryl monooleatealpha-MonooleinGLYCEROL MONOOLEATEGlycerol oleate25496-72-4Nikkol MGOMonoglyceryl oleateOleic monoglycerideGlycerine monooleateOleoylglycerolOlicine

이름 더 보기

글리세롤1-올레이트글리세롤1-올레이트글리세릴올리에이트Glyceryl oleateGMO9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester1-Monooleoylglycerol1-OLEOYL-RAC-GLYCEROL1-OleoylglycerolAblunol GMO

Supeol1-Mono(cis-9-octacenoyl)glycerol2,3-dihydroxypropyl (Z)-octadec-9-enoateSinnoester ogcOleylmonoglycerideExcel O 95FDimodan LSQKEmalsy MO

데이터베이스 식별자

CAS: 111-03-5、25496-72-4
PubChem CID: 5283468
DTXSID: DTXSID3042003
ChEMBL: CHEMBL2075039、CHEMBL428593
ChEBI: CHEBI:75342
UNII: D3AEF6S35P
EC Number: 203-827-7、247-038-6
Nikkaji: J5.104G

물성

구조 계산 물성

XLogP: 6.5
극성 표면적: 66.8 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 4
회전 가능 결합 수: 19
무거운 원자 수: 25
형식 전하: 0
복잡도: 315

실험 및 물리화학적 성질

Chemical ClassesOther Uses -> Emulsifiers/Surfactants

LipidsLipids -> Glycerolipids [GL] -> Monoradylglycerols [GL01] -> Monoacylglycerols [GL0101]

Fragrances · 2건

Fragrance Ingredient (9-Octadecenoic acid (Z)-, monoester with 1,2,3-propanetriol) -> IFRA transparency List

Fragrance Ingredient (Glyceryl monooleate) -> IFRA transparency List

SurfactantsSurfactant

OdorSWEET

TasteFATTY TASTE

물리화학적 성질

녹는점: 35 · 35-37 °C
끓는 점: 409.35 °C · 409.35°C (rough estimate)
밀도: 0.9407 g/cm3 · 0.9407 g/cm3 (35 ºC)
굴절률: 1.46384 · 1.46384 (589.3 nm 35℃)
FEMA: 2526 · 2526 | GLYCERYL MONOOLEATE
인화점: 180 °C · 180 °C
저장 조건: 2 · 2-8°C
용해도: 50 mg/mL, · 클로로포름: 50mg/mL, 투명, 무색
산도 계수 (pKa): 13.16 · 13.16±0.20(Predicted)
물리적 상태: 고체
색상: 흰색에서 황백색까지
냄새: 순한 지방 왁스 같은
냄새 유형: 온화한
생물학적 소스: synthetic (organic)
JECFA Number: 919 · 919
BRN: 1728976 · 1728976
안정성: 흡습성
화장품 원료 기능: 향수계면활성제 - 유화제피부 컨디셔닝 - 보습제
InChI: 1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChIKey: RZRNAYUHWVFMIP-KTKRTIGZSA-N
SMILES: O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
LogP: 6.71 · 6.71
EPA: Glycerol monooleate (111-03-5)

화학적 성질

White Waxy Solid

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 96.9% (492 of 508) of all reports.

Not Classified

Aggregated GHS information provided per 508 reports by companies from 5 notifications to the ECHA C&L Inventory.

This chemical does not meet GHS hazard criteria for 100% (260 of 260) of all reports.

Not Classified

Aggregated GHS information provided per 260 reports by companies from 1 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory Information · 4건

Chemical: 9-Octadecenoic acid, monoester with 1,2,3-propanetriol, (Z)-

9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

1-Glyceryl monooleate: Does not have an individual approval but may be used under an appropriate group standard

Glyceryl monooleate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 9-Octadecenoic acid, monoester with 1,2,3-propanetriol, (Z)-: Human health tier I assessment

Hazards SummaryMay cause mild irritation; [MSDSonline]

FDA Requirements · 2건

SYNTHETIC FLAVOR INGREDIENTS- GLYCERYL MONOOLEATE: REGULATION 172.515.

REGULATION FDA 121.1164; LIMITATIONS: SYNTHETIC FLAVOR.

EPA Safer Chemical · 2건

Chemical: Glyceryl monooleate

Chemical: Glyceryl monooleate [NF]

Hazard Classes and Categories · 2건

Not Classified

독성 정보

Human Toxicity Excerpts · 2건

TREATMENT OF HUMAN ERYTHROCYTE GHOST MEMBRANES WITH THE FUSOGENIC LIPID GLYCEROL MONOOLEATE INCREASED THE FLUIDITY OF THE MEMBRANE LIPIDS, BUT THE NONFUSOGENIC LIPID GLYCEROL MONOSTEARATE HAD NO EFFECT.

IF ANY OF THESE ESTERS IS SIGNIFICANTLY TOXIC, THE ACID PORTION MUST BE HELD RESPONSIBLE, NOT THE GLYCEROL. /GLYCEROL ESTERS/

규제 정보

FDA Requirements · 2건

SYNTHETIC FLAVOR INGREDIENTS- GLYCERYL MONOOLEATE: REGULATION 172.515.

REGULATION FDA 121.1164; LIMITATIONS: SYNTHETIC FLAVOR.

안전 데이터

wgk: 1
tsca: TSCA listed
ridadr: UN 1282 3/PG 2
HS 번호: 29161500
risk_code: 11-20/21/22
hazard_code: F,Xn
safety_code: 36/37
기존화학 물질: KE-26468
F 고인화성물질: 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

Uses · 3건

Used in foods, pharmaceuticals, cosmetics, rust-preventive oils, vinyl light stabilizers, odorless base paints, textile finishing, and flavoring; Used as emulsifier for liquid and paste waxes, polishes, and cleaners; [Hawley]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

SURFACE-ACTIVE AGENT IN FOODS, PHARMACEUTICALS AND COSMETICS, ODORLESS BASE PAINTS, IN RUST-PREVENTIVE OILS, TEXTILE FINISHING, AND VINYL LIGHT STABILIZERS; FLAVORING INGREDIENT

U.S. Exports · 2건

(1972) No Data

(1975) No Data

U.S. Imports · 2건

(1972) No Data

(1975) No Data

U.S. Production · 3건

2023: 5,000,000 - <10,000,000 lb

(1972) 1.25X10+9 GRAMS

(1975) 1.71X10+9 GRAMS

Consumer UsesSurface modifier

Industry UsesLubricating agent

응용 분야 · 2건

용도Glyceryl Monooleate is a flavoring agent that is prepared by esterification of commercial oleic acid that is derived either from edible sources or from tall oil fatty acids. It contains and glyceryl esters of fatty acids present in commercial oleic acid. The ingredient is also used as an adjuvant and as a solvent and vehicle.

일반 설명1-Oleoyl-rac-glycerol is commonly known as monoolein (MO). It is an amphiphilic molecule that is made up of a glycerol backbone and a hydrocarbon chain.