Benzoyl Peroxide → 1-(Bromomethyl)-4-fluoro-2-nitrobenzene
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.[Br:12]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][Br:12])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1참가 물질
5
실험 절차
To a stirred solution of 4-fluoro-2-nitro toluene (48.9 g) and N-bromosuccinimide (56 g) in carbon tetrachloride (300 ml) was added benzoylperoxide (0.78 g). The mixture was heated under reflux for 90 minutes. Additionally, benzoylperoxide (0.78 g) was added to the mixture. Reflux was continued 90 minutes then, cooled to room temperature.
후처리
- temperatureThe mixture was heated
- temperatureunder reflux for 90 minutes
- temperatureReflux
출처 및 근거
- ORD 기록
- ord-75f22451642547eba7d5a1a1f12a4943
- 출처 데이터셋
- uspto-grants-1996_04
- 특허 번호
- US05504095
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