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Hydrochloric Acid → HCID 70094289, 화합물

HRID 1720861
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HRID 1720861 반응식
[CH2:1]([O:3][C:4](=[O:28])[C@H:5]([CH2:20][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1)[NH:6][C:7](=[O:19])[C:8]([NH:11]C(OC(C)(C)C)=O)([CH3:10])[CH3:9])[CH3:2].[ClH:29]>C(OCC)(=O)C.CO>[ClH:29].[CH2:1]([O:3][C:4](=[O:28])[C@H:5]([CH2:20][C:21]1[CH:22]=[CH:23][C:24]([OH:27])=[CH:25][CH:26]=1)[NH:6][C:7](=[O:19])[C:8]([NH2:11])([CH3:10])[CH3:9])[CH3:2]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 10810636N-[2-(t-butoxycarbonylamino)-2-methyl-1-oxopropyl]-L-tyrosine ethyl ester

생성물 1

HCID 70094289HCID 70094289, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 8857Ethyl Acetate용매

실험 절차

Into a stirred solution of N-[2-(t-butoxycarbonylamino)-2-methyl-1-oxopropyl]-L-tyrosine ethyl ester (1.46 g, 3.70 mmol) in ethyl acetate (50 mL) and methanol (10 mL) is bubbled hydrochloric acid gas for 10 minutes. The solvent is removed to give N-(2-amino-2-methyl-1-oxopropyl)-L-tyrosine ethyl ester monohydrochloride as a white foam which is used without any further purification.

후처리

  1. customThe solvent is removed

출처 및 근거

ORD 기록
ord-e251d246b4a14d508861620eaf3e7df8
출처 데이터셋
uspto-grants-1996_04
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05508266

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