Dicyclohexylcarbodiimide → N,N'-Dicyclohexylurea

Dehydro-ryanodine (60 mg., 0.125 mmol), N-(p-n-butoxybenzoyl)-β-alanine (40 mg. 0.15 mmol) and DMAP (2 mg., 0.02 mmol), dried over P2O5, were dissolved in a solvent mixture of CH2Cl2 (10 ml.) and tetrahydrofuran (0.1 ml) dried over Molecular Sieve. To the stirred solution dicyclohexylcarbodiimide (35 mg., 0.15 mmol) was added at once and the reaction mixture maintained at room temperature for 6 hours. Water (0.1 ml) was added and stirring continued for 30 minutes. The solids formed (dicyclohexylurea) were filtered and washed twice with CH2Cl2.

1. customdried over Molecular Sieve

ORD 기록

ord-8b8926540b0b4f57af3974500ec01a84

출처 데이터셋

uspto-grants-1996_04

DOI

10.6084/m9.figshare.5104873.v1

특허 번호

US05510500