Heptafluorobutyryl Chloride → Heptafluorobutyraldehyde

HRID 1721698

반응식

HRID 1721698 반응식
C([SiH](C(C)C)C(C)C)(C)C.[C:11]([C:15]([C:18]([C:21](Cl)=[O:22])([F:20])[F:19])([F:17])[F:16])([F:14])([F:13])[F:12]>[Pd]>[C:18]([CH:21]=[O:22])([C:15]([C:11]([F:12])([F:13])[F:14])([F:17])[F:16])([F:20])[F:19]

참가 물질

4

반응물 2

HCID 67810Heptafluorobutyryl ChlorideHCID 138754Silane, tris(1-methylethyl)-

생성물 1

HCID 67809Heptafluorobutyraldehyde수율 64.4%

시약·촉매·용매 1

HCID 23938Palladium촉매

반응 조건

온도
0 °C

실험 절차

A 3-necked round bottom flask fitted with with dropping funnel, dry-ice condenser, and gas inlet was charged with 10% Pd/C (0.35 g) and cooled to 0° C. Triisopropylsilane (7.29 g, 46 mmol) was added, and CF3CF2CF2C(O)Cl (9.30 g, 40 mmol) was added dropwise over a 10 min period. The reactor was connected to a cold trap (-78° C.) while the mixture was stirred for 18 hr. Transfer from the trap and reaction vessel gave a total of 5.1 g (62%) of colorless liquid. 1H NMR (CD2Cl2): 9.62 (m). 19F NMR: -81.24 (t, J=8.3 Hz), -126.4 (quartet of doublets, Jq =8.3, Jd =3.2), -127.9 (s).

후처리

  1. customA 3-necked round bottom flask fitted with
  2. customThe reactor was connected to a cold trap
  3. customTransfer from the trap and reaction vessel

출처 및 근거

ORD 기록
ord-0fccc08b2fc14cf4a3ac589015292dd5
출처 데이터셋
uspto-grants-1996_04
특허 번호
US05512652

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