Nitrogen → N-(3-(Trimethoxysilyl)propyl)acrylamide

HRID 1723500

반응식

HRID 1723500 반응식
N#N.[NH2:3][CH2:4][CH2:5][CH2:6][Si:7]([O:12][CH3:13])([O:10][CH3:11])[O:8][CH3:9].C[O-].[Na+].[C:17](Cl)(=[O:20])[CH:18]=[CH2:19]>C1(C)C=CC=CC=1.CO>[C:17]([NH:3][CH2:4][CH2:5][CH2:6][Si:7]([O:12][CH3:13])([O:8][CH3:9])[O:10][CH3:11])(=[O:20])[CH:18]=[CH2:19]

참가 물질

7

반응물 4

HCID 947NitrogenHCID 13140Acryloyl chlorideHCID 83756AminopropyltrimethoxysilaneHCID 10942334Sodium Methoxide

생성물 1

HCID 13879166N-(3-(Trimethoxysilyl)propyl)acrylamide

시약·촉매·용매 2

HCID 887Methanol용매HCID 1140Toluene용매2회

반응 조건

온도
0 °C

실험 절차

A one liter, three-necked flask equipped with a thermometer, stirring paddle, air tight stirring sleeve, N2 inlet and dropping funnel was charged with aminopropyltrimethoxysilane (100.0 g, 0.558 moles), toluene (160.1 g), sodium methoxide (33.16 g, 0.614 moles) and methanol (10.11 g). The mixture was stirred under N , atmosphere and cooled to 0° C using a dry ice/isopropanol bath. To this, 55.37 g (0.614 moles) of acrylyl chloride dissolved in 100 g of toluene was added gradually over a period of 30 minutes. The mixture was agitated for another 30 minutes. By-product sodium chloride was removed by filtration and the solvent was removed under reduced pressure to obtain acrylamidopropyltrimethoxysilane in essentially quantitative yield. Sodium nitrite (0.001 g) was added as an inhibitor.

후처리

  1. customA one liter, three-necked flask equipped with a thermometer
  2. additionwas added gradually over a period of 30 minutes
  3. stirringThe mixture was agitated for another 30 minutes
  4. customBy-product sodium chloride was removed by filtration
  5. customthe solvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-4b6ce1266536461bb141d496d34ec9dd
출처 데이터셋
uspto-grants-1989_08
특허 번호
US04861906

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