Water → HCID 69067984, 화합물
반응식
[C:1]1([C:7]2[O:8][C:9]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:10][C:11]=2[C:12]#N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH2:20].[OH-:21].[Na+]>C(O)CO>[C:1]1([C:7]2[O:8][C:9]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:10][C:11]=2[C:12]([OH:21])=[O:20])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
5
실험 절차
A suspension of 2,5-diphenylfuran-3-carbonitrile (0.87 g, 3.56 mmol) in ethylene glycol and 3M NaOH (10 ml) was heated at reflux for 3 days. Water was added to the reaction mixture and extracted into CH2Cl2. The organic layer was dried with MgSO4, filtered and concentrated to provide 2,5-diphenylfuran-3-carboxylic acid (intermediate XXVIf, 900 mg) as white solid.
후처리
- temperaturewas heated
- temperatureat reflux for 3 days
- extractionextracted into CH2Cl2
- dry with materialThe organic layer was dried with MgSO4
- filtrationfiltered
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-f3213b59182c4e2b82865e4edc8b0ada
- 출처 데이터셋
- uspto-grants-2009_02
- 특허 번호
- US07491821B2
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