Sodium Hydroxide → (3-Hydroxy-4-propionyl-2,6-dipropyl-phenoxy)-phenyl-acetic acid

반응식

[OH:1][C:2]1[C:3]([CH2:27][CH2:28][CH3:29])=[C:4]([C:17]([CH2:24][CH2:25][CH3:26])=[CH:18][C:19]=1[C:20](=[O:23])[CH2:21][CH3:22])[O:5][CH:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([O:9]C)=[O:8].[OH-].[Na+]>>[OH:1][C:2]1[C:3]([CH2:27][CH2:28][CH3:29])=[C:4]([C:17]([CH2:24][CH2:25][CH3:26])=[CH:18][C:19]=1[C:20](=[O:23])[CH2:21][CH3:22])[O:5][CH:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([OH:9])=[O:8]

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 21985968Methyl alpha-[3-hydroxy4-(1-oxopropyl)-2,6-dipropylphenoxy]benzeneacetate

생성물 1

HCID 21985914(3-Hydroxy-4-propionyl-2,6-dipropyl-phenoxy)-phenyl-acetic acid

실험 절차

The ester of step 2 (18.6 gm) was hydrolyzed with NaOH (98 ml) as for example 1, step 5.

출처 및 근거

ORD 기록: ord-f11488e1286241a5b9da2dc311a5baa9
출처 데이터셋: uspto-grants-2009_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07495020B2

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