2,2'-Bis(bromomethyl)-1,1'-biphenyl → 2,2'-Dimethylbiphenyl

HRID 1729483

반응식

HRID 1729483 반응식
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15]Br>C1COCC1>[C:10]1([CH3:15])[C:9]([C:4]2[C:3]([CH3:2])=[CH:8][CH:7]=[CH:6][CH:5]=2)=[CH:14][CH:13]=[CH:12][CH:11]=1

참가 물질

3

반응물 1

HCID 2519622,2'-Bis(bromomethyl)-1,1'-biphenyl

생성물 1

HCID 117972,2'-Dimethylbiphenyl

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

2,2'-Bis(bromomethyl)-1,1'-biphenyl (3.40 grams, 10 mmole) was added to the addition funnel and dissolved in 10 mL of dry THF. The dibromo compound may be obtained by the free radical catalyzed halogenation of 2,2'-bitolyl. The flask containing the dibenzophospholyl anion is chilled with a water-ice bath. The mixture was stirred vigorously as the dibromo compound was added dropwise to the chilled solution over 30 minutes. The solution color lightened by the end of the addition. The resulting mixture was allowed to stir at room temperature for an additional five hours. Methanol (5 mL) was added to quench out any remaining anion and resulted in a pale yellow mixture.

출처 및 근거

ORD 기록
ord-d547631849664859b8132ec7d2eaff8c
출처 데이터셋
uspto-grants-1994_07
특허 번호
US05332846

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