Hydrochloric Acid → 3-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl)-N-propylpropionic acid amide

HRID 1730000

반응식

HRID 1730000 반응식
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[CH2:15]([NH:18][C:19](=[O:22])[CH:20]=[CH2:21])[CH2:16][CH3:17].Cl>>[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][N:11]([CH2:21][CH2:20][C:19]([NH:18][CH2:15][CH2:16][CH3:17])=[O:22])[CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 114794N-(n-Propyl) acrylamideHCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

생성물 1

HCID 681390763-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl)-N-propylpropionic acid amide

실험 절차

1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine and N-propyl acrylamide are reacted in accordance with the process described in Example 6. Reaction period 20 hours. M.P. of the hydrochloride of the title compound 196°-197° from ethanol (decomp.).

후처리

  1. customReaction period 20 hours

출처 및 근거

ORD 기록
ord-009868a82a694d1abeb2207a81ff6de5
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03991066

연결된 노트

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