Hydrochloric Acid → N-n-Butyl-3-(1,3,4,9b-tetrahydro-5-methyl-2H-indeno [1,2-c]pyridin-2-yl) propionic acid amide

HRID 1730001

반응식

HRID 1730001 반응식
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[CH2:15]([NH:19][C:20](=[O:23])[CH:21]=[CH2:22])[CH2:16][CH2:17][CH3:18].Cl>>[CH2:15]([NH:19][C:20](=[O:23])[CH2:21][CH2:22][N:11]1[CH2:12][CH2:13][C:14]2=[C:2]([CH3:1])[C:3]3[C:8]([CH:9]2[CH2:10]1)=[CH:7][CH:6]=[CH:5][CH:4]=3)[CH2:16][CH2:17][CH3:18]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 642908n-Butyl-2-propenamideHCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

생성물 1

HCID 54086914N-n-Butyl-3-(1,3,4,9b-tetrahydro-5-methyl-2H-indeno [1,2-c]pyridin-2-yl) propionic acid amide

실험 절차

1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine and N-n-butyl acrylamide are reacted in accordance with the process described in Example 6. Reaction period 14 hours. M.P. of the hydrochloride of the title compound 193°-194° from ethanol (decomp.).

후처리

  1. customReaction period 14 hours

출처 및 근거

ORD 기록
ord-37fc2981881f45c78198ea52b9a978f1
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03991066

연결된 노트

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