Hydrochloric Acid → N-Benzyl-3-(1,3,4,9b-tetrahydro-5-methyl-2H-indeno [1,2-c]pyridin-2-yl) propionic acid amide

HRID 1730004

반응식

HRID 1730004 반응식
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[CH2:15]([NH:22][C:23](=[O:26])[CH:24]=[CH2:25])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.Cl>>[CH2:15]([NH:22][C:23](=[O:26])[CH2:24][CH2:25][N:11]1[CH2:12][CH2:13][C:14]2=[C:2]([CH3:1])[C:3]3[C:8]([CH:9]2[CH2:10]1)=[CH:7][CH:6]=[CH:5][CH:4]=3)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 139428N-BenzylacrylamideHCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

생성물 1

HCID 54446244N-Benzyl-3-(1,3,4,9b-tetrahydro-5-methyl-2H-indeno [1,2-c]pyridin-2-yl) propionic acid amide

실험 절차

1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine and N-benzyl acrylamide are reacted in accordance with the process described in Example 6. Reaction period 8 hours. M.P. of the hydrochloride of the title compound 211°-212.5° from ethanol (decomp.).

후처리

  1. customReaction period 8 hours

출처 및 근거

ORD 기록
ord-d4a7e82db84740a19901898f3390d3eb
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03991066

연결된 노트

불러오는 중…